Obesity Harming Strides Made Against Heart Disease

TUESDAY, 2019 (HealthDay News) -- obesity rates, appears to undoing decades of gains against heart disease, the of from heart continued Obesity Harming Strides to drop, from high pressure increased, because despite medical surgical advances public initiatives around cholesterol pressure awareness," said lead Dr. Sadiya Khan. She is an assistant of cardiology at Northwestern Feinberg School of Medicine," added," Khan said.

A newly developed technique that shows artery clogging fat-and-protein complexes in live fish gave investigators from Carnegie, Johns Hopkins University, and the Mayo Clinic a glimpse of how to study heart disease in action. Their research, which is currently being used to find new drugs to fight cardiovascular disease, is now published in Nature Communications. Fat molecules, also called lipids, such as cholesterol and triglycerides are shuttled around the circulatory system by a protein called Apolipoprotein-B, or ApoB for short. These complexes of lipid and protein are called lipoproteins but may be more commonly known as "bad cholesterol and heart disease cholesterol. " Sometimes this fat-and-cholesterol ferrying apparatus stops in its tracks and embeds itself in the sides of blood vessels, forming a dangerous buildup. Called plaque, these deposits stiffen the wall of an artery and makes it more difficult for the heart to pump blood, which can eventually lead to a heart attack. "These ApoB-containing lipoproteins are directly responsible for creating plaques in blood vessels, so learning more about them is essential to fighting the global epidemic of cardiovascular disease," explained lead author James Thierer a graduate student at Johns Hopkins who does research at Carnegie's Department of Embryology.

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